The Clemson Tigers (3-5) meet a fellow ACC opponent when they host the Florida State Seminoles (4-4) on Saturday, November 8, 2025 at Memorial Stadium (Clemson, SC).

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Clemson vs. Florida State Matchup Info

Game date: Saturday, November 8, 2025
Game time: 7 p.m. ET
Location: Clemson, South Carolina
Venue: Memorial Stadium (Clemson, SC)
TV channel: ACC Network
Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Clemson vs. Florida State Odds and Prediction

Spread favorite: Tigers (-1.5)
Moneyline: Tigers (-119), Seminoles (-101)
Total: 56.5 points
Pick ATS: Florida State (+1.5)
Pick OU: Under (56.5)
Prediction: Florida State 34, Clemson 22

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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Clemson vs. Florida State Betting Records and Insights

Clemson has won just two games against the spread this season.
Florida State has won three games against the spread this year, failing to cover four times.
The Tigers have covered the spread twice when favored by 1.5 points or more this season (in eight opportunities).
The Seminoles have covered the spread once this year (1-1 ATS) when playing as at least 1.5-point underdogs.
A total of four out of eight Clemson games this season have hit the over.
So far this year, four of Florida State's seven games with a set number have hit the over.

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