The No. 23 Missouri Tigers (3-0) host an SEC clash against the South Carolina Gamecocks (2-1) on Saturday, September 20, 2025 at Memorial Stadium/Faurot Field.
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Missouri vs. South Carolina Matchup Info
- Game date: Saturday, September 20, 2025
- Game time: 7 p.m. ET
- Location: Columbia, Missouri
- Venue: Memorial Stadium/Faurot Field
- TV channel: ESPN
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Missouri vs. South Carolina Odds and Prediction
- Spread favorite: Tigers (-10)
- Moneyline: Tigers (-351), Gamecocks (+275)
- Total: 48.5 points
- Pick ATS: South Carolina (+10)
- Pick OU: Over (48.5)
- Prediction: Missouri 30, South Carolina 22
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Missouri vs. South Carolina Betting Records and Insights
- Missouri has put together a perfect 3-0-0 record against the spread this season.
- South Carolina has a record of 1-2-0 against the spread this year.
- The Tigers have been favored by 10 points or more two times this season, and covered the spread in both.
- So far this season, each Missouri game has gone over the point total.
- So far this season, no South Carolina game has gone over the point total.