The No. 11 South Carolina Gamecocks (2-0) square off against a conference opponent when they host the Vanderbilt Commodores (2-0) on Saturday, September 13, 2025 at Williams-Brice Stadium in an SEC clash.
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South Carolina vs. Vanderbilt Matchup Info
- Game date: Saturday, September 13, 2025
- Game time: 7:45 p.m. ET
- Location: Columbia, South Carolina
- Venue: Williams-Brice Stadium
- TV channel: SEC Network
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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South Carolina vs. Vanderbilt Odds and Prediction
- Spread favorite: Gamecocks (-3)
- Moneyline: Gamecocks (-159), Commodores (+134)
- Total: 48.5 points
- Pick ATS: Vanderbilt (+3)
- Pick OU: Over (48.5)
- Prediction: South Carolina 26, Vanderbilt 24
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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South Carolina vs. Vanderbilt Betting Records and Insights
- South Carolina has covered once in two games with a spread this season.
- Vanderbilt has won all two of its games against the spread this season.
- The Gamecocks have covered the spread once when favored by 3 points or more this season (in two opportunities).
- So far this season, one Vanderbilt game has hit the over.